Sublime Silva leads City to record-breaking win

first_imgSwansea City 0 Manchester City 4: Silva sparkles as Guardiola’s record-breakers march on Guy Atkinson Last updated 1 year ago 05:40 12/14/17 David Silva - cropped Getty Images David Silva scored twice to help Manchester City to a routine – and record-breaking win – over Swansea City. Manchester City cruised past Swansea City 4-0 at the Liberty Stadium on Wednesday to set a new Premier League record of 15 consecutive wins.Pep Guardiola’s runaway league leaders set a new best mark for an individual season when they beat Manchester United 2-1 on Sunday and have now overtaken Arsenal’s 14-game streak, which was registered across two campaigns. Two goals from the irrepressible David Silva and one each from Kevin De Bruyne and Sergio Aguero sealed a routine triumph over the league’s bottom club, maintaining City’s enormous lead over United at the summit. Article continues below Editors’ Picks Lyon treble & England heartbreak: The full story behind Lucy Bronze’s dramatic 2019 Liverpool v Man City is now the league’s biggest rivalry and the bitterness is growing Megan Rapinoe: Born & brilliant in the U.S.A. A Liverpool legend in the making: Behind Virgil van Dijk’s remarkable rise to world’s best player Silva, who grabbed the opener against United at the weekend, got City up and running after 27 minutes with a clever finish before De Bruyne continued his remarkable season by scoring with a free-kick. Spain international Silva grabbed his second shortly after the restart with another fine finish and only some impressive saves from Lukasz Fabianksi prevented the scoreline from spiralling out of control.13 – David Silva has been involved in 13 Premier League goals in 17 games this season (five goals, eight assists) – already more than in the whole of 2016-17 (11 goal involvements in 34 games). Service.— OptaJoe (@OptaJoe) December 13, 2017Sergio Aguero completed another memorable night for Guardiola’s record-breakers late on, finishing a mazy run with a wonderful finish into the bottom corner. City, who made four changes from the game at Old Trafford, started in typically dominant fashion and came close early on when Fernandinho’s sweetly struck volley was repelled by Fabianski.The visitors were far from their fluid best in the opening quarter – with just two off-target Aguero headers to show for their efforts – but deservedly broke the deadlock shortly before the half-hour mark..Bernardo Silva’s teasing cross was inexplicably left by the Swans backline and his namesake, David, was on the receiving end to impudently flick past the exposed Fabianksi.Bernardo & David— Benjamin Mendy (@benmendy23) December 13, 2017It took just seven more minutes for City to bag their second as De Bruyne’s dipping free-kick from the corner of the penalty area bounced awkwardly in front of Fabianski and flashed past him into the net. Silva should have scored his second immediately after the interval, but somehow contrived to skew wide after lovely interplay between De Bruyne and Aguero had released him inside the area.Aguero was then denied by Fabianksi before Silva atoned for that earlier miss with a goal of the highest quality.The 31-year-old collected Raheem Sterling’s pass inside the area, moved the ball out of his feet, and clipped a wonderful finish over the onrushing Fabianski for his fifth goal of the season.The horribly over-worked Swans goalkeeper made a fine save from Sterling just moments later and Aguero flashed wide as City threatened to run riot. Aguero did finally get on the scoresheet with five minutes remaining as he blazed past the beleaguered Swans defence and stroked into the bottom corner – a fitting way to end a landmark evening for Guardiola’s men.Key Opta Stats:- Manchester City have set a new outright record of 15 consecutive wins in the English top-flight. This is also an outright record within the top four tiers of English league football.- Based on three points for a win, Manchester City have made the outright best start ever to an English top-flight season after 17 games (49 points).- Manchester City have won the same number of games in this current winning run (15) as Swansea City have in their 55 Premier League matches since the start of last season.- This Manchester City winning run (15 in a row) is still four wins away from Pep Guardiola’s best-ever winning run as a manager in league competition. He won 19 in a row between October 2013 and March 2014 as Bayern Munich boss in the Bundesliga.- David Silva has been involved in 13 Premier League goals in 17 games this season (five goals, eight assists) – already more than in the whole of 2016-17 (11 goal involvements in 34 games).- Sergio Aguero scored his 10th Premier League goal of the season – he has now reached double figures in all seven of his seasons as a Premier League player. read morelast_img read more

admin November 16, 2019 xzatoksixeja Leave a Comment

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Nautilus Urges UK to Tackle Seafarer Exploitation

first_imgzoom In the light of new figures showing exploitation in the shipping industry is widespread, the maritime trade union Nautilus International has called on the UK government to address the issue.The union has again warned of the plight of seafarers working on foreign-flagged ships in British waters, who are receiving minimal or no pay and “suffering atrocious conditions” following the publication of a report from the National Crime Agency (NCA) showing there are as many as 13,000 victims of modern slavery in the UK, with some 300 current policing operations.Nautilus recently highlighted the deplorable conditions seafarers suffered onboard a Turkish ship detained in the UK port of Runcorn. The crew, who were being paid wages as low as USD 0.85 an hour, had to endure a cockroach infestation, had no fresh food and were found to be owed almost USD 74,000 in back pay following checks by Nautilus/ITF inspector Tommy Molloy.As a result, the Maritime & Coastguard Agency (MCA) and the UK Border Force detained the vessel for a number of health and safety violations directly related to the substandard conditions onboard. After the expiration of the crew’s leave of stay, they had effectively become illegal workers with no protections and faced deportation. The combined efforts of the Nautilus/ITF inspector, the MCA and the UK Border Force finally resulted in payment of owed wages and the repatriation of the seafarers to their homes following lengthy prevarication by the vessel’s operator, Voda Shipping of Turkey, according to Nautilus.“We’re calling on the government to affirm its commitments in tackling modern slavery in the shipping industry. There is an “out of sight and out of mind” attitude towards conditions in some parts of the industry where seafarers are being exploited, but it won’t come as a surprise to those working in the industry that these practices are happening,” Mark Dickinson, Nautilus general secretary, said.Despite the Modern Slavery Act, which came into law in 2015, and international legislation, “we’re finding that some shipowners are continuing to profiteer at the expense of crew,” Dickinson added.last_img read more

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South West Health To Test Cancer Education Program

first_img Cancer patients, their families and health-care workers in SouthWest Health have a new tool designed to help them through thevarious stages of the disease. Cancer Care Nova Scotia today, Oct. 7, announced the introductionof the Oncology Interactive Education Series (OIES), aninteractive, computer-based cancer-education program forpatients, their families and health professionals. The program was developed in Canada by Jack Digital Productionsin collaboration with Toronto’s Princess Margaret Hospital. NovaScotia is the first province to test it. South West Health is oneof the five health districts piloting the program. “Hearing the words, ‘you have cancer,’ is traumatic,” said Dr.Andrew Padmos, commissioner, Cancer Care Nova Scotia. “There areso many questions, so many fears, many of which can be alleviatedif patients have access to quality cancer information.Information puts people back in the driver’s seat. It helps themunderstand their treatment options and make informed decisions. “For health professionals, access to quality patient educationhelps them support their patients. And, research also indicatesthat it leads to a better understanding of the illness, bettercompliance with treatment and thus better outcomes. OIES willrespond to the needs that patients, families and healthprofessionals have identified and ultimately lead to bettercancer care.” Each of the 24 cancer-type specific titles in the series containsbetween 18 and 25 hours of information. Each topic follows thepatient experience, providing information about diseaseprevention, early detection, symptoms, diagnosis, staging,treatment options, nutrition, pain management, psychosocial careand community support services. It also provides answers to anumber of commonly asked questions. The learning is supported bythree dimensional anatomy, patient experiences and cleargraphics. “We are very pleased to have the Oncology Interactive EducationSeries available in South West Health,” said patient navigatorDarolyn Walker. “It has become a valuable resource to both healthprofessionals and patients who are seeking quality cancerinformation.” OIES is designed to meet the need of a broad range of learningstyles, computer experience, literacy levels and language skills.Trained volunteers will help patients, families and healthprofessionals to use OIES. Patients who have access to a computermay also borrow titles from the program’s lending libraries. OIES will be evaluated to measure the use of the tool bypatients, families and health professionals, as well as theirsatisfaction with it. The evaluation will also seek healthprofessionals’ opinions on how best to use the teaching tool aspart of the care process. The decision to implement OIES acrossthe province will be based on evaluation results, which areexpected to be available in June 2005. Cancer Care Nova Scotia is a program of the Department of Health,created to reduce the burden of cancer on individuals, familiesand the health-care system through prevention, screening,education and research. CANCER CARE N.S.–South West Health To Test Cancer EducationProgramlast_img read more

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Crime Prevention Experts Come Together to Improve Safety

first_imgHundreds of Atlantic Canadians committed to preventing and reducing crime will come together in May with the goal of making our schools and communities safer. The 25th Annual Atlantic Crime Prevention Conference is being held in Halifax, May 4-6. The theme is Safe Schools – Strong Communities: A Crime Prevention Approach. It is a partnership of the Department of Justice, Crime Prevention Societies of Nova Scotia, the National Crime Prevention Center and the Atlantic Coordinating Committee on Crime Prevention. “We are committed to making this province safer for individuals, families and communities,” said Ross Landry, Minister of Justice. “Of recent concern is the issue of Internet bullying and the safety of our young people. “With a focus on school safety, this conference will be a timely opportunity to learn from others across Atlantic Canada and work together to make our schools, and our communities safer.” A workshop on cyber-bullying and Internet luring will be just one of many sessions attended by more than 200 people involved in crime prevention including, teachers, police officers, academic researchers, community members, municipal leaders, policy advisors, social workers and many others. The goals of the 2011 conference are to raise awareness of good practices and programs that can address, improve and promote a safer school environment, and to provide tools to help improve community safety. “The most important thing about this conference is the opportunity to connect the crime prevention and community safety advocates with educators and leaders,” said Ken MacDonald, conference co-chair. “This is a chance for them to work together and explore options and strategies to make their communities and neighborhoods more safe.” The Annual Minister’s Award for Leadership in Crime Prevention will also be presented at the conference. For more information about the conference or to register online, visit read more

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Sultry day in Delhi heavy rain likely on Tuesday

first_imgNew Delhi: It was a sultry day in the national capital on Monday with the maximum temperature settling two notches above normal at 35.5 degrees Celsius. “The minimum temperature settled at 25.7 degrees Celsius, normal for this time of the year,” a Met official said. The Safdarjung observatory received 2.8 mm rainfall while the Ridge area recorded 5.2 mm rainfall. The Palam observatory, Lodhi Road and Aya Nagar observatories recorded nil rainfall on Monday. The weatherman has forecast heavy rain for Tuesday and the maximum and minimum temperatures are likely to settle around 36 and 26 degrees Celsius respectively. On Sunday, the minimum temperature was recorded at 28 degrees Celsius, while the maximum temperature was 36.2 degrees Celsius.last_img read more

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Enbridge Line 3 project should follow existing route US judge says

first_imgMINNEAPOLIS – Minnesota regulators should approve Enbridge Energy’s proposal for replacing its aging Line 3 crude oil pipeline only if it follows the existing route rather than company’s preferred route, an administrative law judge recommended Monday.The proposal has drawn strong opposition because Enbridge’s preferred route would carry oilsands crude from Alberta across environmentally sensitive areas in the Mississippi River headwaters region where American Indians harvest wild rice and hold treaty rights.Administrative Law Judge Ann O’Reilly’s recommendation that the Public Utilities Commission should order that the replacement follow the existing route sets up further disputes, however, because the existing line crosses two Ojibwa reservations where tribal governments have made it clear that they won’t consent and want the old line removed altogether.O’Reilly wrote that Enbridge has established that the project is needed, but that the negative consequences to Minnesota of the company’s more southerly preferred route outweigh the benefits. The cost-benefit analysis shifts in favour of approving the project if Enbridge builds the pipeline in Line 3’s existing trench, she said.The commission is expected to make its final decision in June. O’Reilly’s recommendations aren’t binding on the commission, but they’re the product of an extensive public hearing and comment process and voluminous filings, so they’ll be hard for the commissioners to disregard. Commission Chair Nancy Lange acknowledged at a hearing last month that whatever the commission decides, the dispute is likely to end up in court.Enbridge said in a statement that it was pleased the judge listened to the extensive evidence for the need for the project, and will be taking time to review the recommendation that it use the existing right-of-way.Environmental and tribal groups — including the Sierra Club, Greenpeace USA and Honor the Earth — said there’s no good reason to allow Enbridge to build the project, regardless of what route it takes.If the project is approved, some opponents have threatened a repeat of the protests in North Dakota near the Standing Rock reservation that delayed work for months on the Dakota Access pipeline, in which Enbridge owns a stake. Similar concerns over the role of the oilsands in climate change, and Indigenous rights, have fuelled opposition to Kinder Morgan’s proposal to expand its Trans Mountain pipeline from Alberta to an export terminal in British Columbia.Calgary-based Enbridge says the Line 3 project is necessary to ensure the reliable delivery of crude to Midwestern refineries. The company says the existing line, which was built in the 1960s, is subject to corrosion and cracking and can run at only half its original capacity because of its accelerating maintenance needs. The Jobs for Minnesotans coalition of business, labour and community leaders backs the project, saying it will create 8,600 well-paying jobs with a total economic impact on the state of $2 billion.Line 3 carries crude oil 1,765 kilometres from Hardisty, Alta., through North Dakota and Minnesota to Enbridge’s terminal in Superior, Wis. Enbridge said the replacement would restore its original capacity of 760,000 barrels per day. Enbridge wants to shift much of the last half of the current 454-kilometre route in Minnesota into a more southerly, 542 kilometre corridor to Superior. Enbridge estimates the cost of the project at $5.3 billion for the Canadian stretch and US$2.9 billion for the U.S. portion.Enbridge has already begun work in Canada and Wisconsin. Construction sites near Superior have been the scene of protests and several arrests.last_img read more

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CORRECTED Grande Prairie police looking for taxi that allegedly struck pedestrian in

first_imgCORRECTION: Cst. Melanie McIntosh with the Grande Prairie RCMP has issued the following clarification about Monday’s release: “RCMP would like to clarify that the suspect vehicle is yellow in colour and it is unknown if it is associated with a company.”GRANDE PRAIRIE, A.B. – Mounties in Grande Prairie RCMP are seeking the public’s help in locating a suspect involved in a hit and run.According to RCMP Cst. Melanie McIntosh, a nineteen-year-old man was hit from behind by a cab while walking southbound on 93A St. near 108 Ave between 9:00 and 10:00 a.m. on February 21st. After hitting the man, the vehicle left the scene and turned westbound on 108th Ave. The man suffered minor injuries in the collision. Cst. McIntosh said that the suspect vehicle is described as a yellow taxicab with tinted windows and checkers on its side.Anyone with information about the incident is asked to call the Grande Prairie RCMP at 780-830-5700. If you would like to remain anonymous, you can contact Crime Stoppers by phone at 1-800-222-8477 or via the Internet at read more

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Australian opposition to discuss asylum issue with Sri Lanka

The visit is also a response to the recent surge of asylum-seeker boats coming from south Asia, particularly Sri Lanka. The spike comes more than three years after the end of Sri Lanka’s civil war, which saw an initial, but temporary, exodus of refugees to Australian shores. News of the planned Sri Lanka visit by immigration spokesman Scott Morrison and foreign affairs spokeswoman Julie Bishop came as Australian opposition leader Tony Abbott last night raised the broader people-smuggling problem at a meeting with Indonesian President Susilo Bambang Yudhoyono in Jakarta. “These visits and these meetings provide important relationship-building and context for policies that we would hope to implement if we were elected,” Mr Morrison said.The Sri Lankan government, he said, had indicated it would be very happy to receive the brace of opposition frontbenchers.With Sri Lanka’s bloody civil war over and claims those travelling from the island were economic refugees, Mr Morrison said there was now no reason not to work with the Sri Lankan government to return boats, provided safeguards were in place to ensure the safety of those returned. Speaking from Jakarta, where he is travelling as part of Abbott’s delegation, Morrison said he and Bishop would visit Colombo within months, the news report said. “We’ve still got to work through the details but it’s our plan to get there before parliament comes back next year,” he told The Australian.He said the visit would be a prelude to the discussions a future Coalition government would initiate as part of its policy of intercepting Sri Lankan asylum-seeker boats in international waters and returning them to their country of departure. Two senior Australian opposition frontbenchers will travel to Sri Lanka to discuss the Coalition’s controversial policy of returning asylum-seeker boats to Sri Lanka, The Australian newspaper reported today.Amid growing signs the revived Pacific Solution is failing to deter asylum-seekers, the Coalition indicated it planned to continue its unorthodox strategy of pursuing foreign policy from opposition. read more

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The Latest Lords clear way for nodeal bill to pass in days

LONDON — The Latest on Britain’s bid to leave the European Union (all times local):7:30 a.m.A bill blocking a no-deal Brexit is on course to pass into law before Parliament is suspended next week.The British Parliament’s upper chamber, the House of Lords, voted early Thursday to push through the bill.The bill’s supporters had feared its opponents in the Lords could try to stop it by filibustering.But in a session that lasted until 1.30 a.m. in London, peers agreed to return the bill to the Commons on Monday for any amendments before passing into law.Lawmakers in the House of Commons hope to pass the bill into law — a process that can take months — in days because Prime Minister Boris Johnson plans to suspend Parliament at some point next week until Oct. 14.Johnson is looking for ways to bring about a national election after rebellious British lawmakers moved to block his plan to leave the European Union next month without a divorce deal and rejected his call to trigger a snap poll.___5:25 a.m.Prime Minister Boris Johnson is looking for new ways to bring about a national election after rebellious British lawmakers rejected his call to trigger a snap poll and moved to block his plan to leave the European Union next month without a divorce deal.Events have spiraled out of Johnson’s control. He leads a government with no majority in Parliament and may not be able to secure an election that could change that fact.The latest setback for Johnson came Wednesday evening after he called for a national election on Oct. 15, saying it was the only way out of Britain’s Brexit impasse after lawmakers moved to block his plan to leave the European Union next month without a divorce deal.But Parliament turned down his motion and the prime minister indicated he would try again, saying an election was the only way forward for the country and urging opposition lawmakers to “reflect overnight and in the course of the next few days.”___Follow AP’s full coverage of Brexit and British politics at: Associated Press read more

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Reindeer becoming smaller due to global warming research finds

first_imgThe implications are that there may well be more smaller reindeer in the Arctic in the coming decadesProfessor Steve Albon However, warmer winters have brought with them greater rainfall which freezes when it settles on the snow, thereby locking out the reindeer from the life-sustaining food below.As a result, female reindeer are becoming starved, causing them to abort their calves or giving birth to much lighter young.The average mass of an adult reindeer in 1994, when the survey began, was 55kg, but by 2010 it had dropped to 48kg.Professor Steve Albon, an ecologist at the James Hatton Institute in Aberdeen, said his the research some of the critical changes facing Arctic species.“While I doubt we will see the extinction of reindeer across their circumpolar range, Santa may need more to pull the laden sleigh,” he joked.He added that, because the mammals have a relatively high surface-area-to-volume ratio, they are no particularly energy efficient.Reindeer can often access the meagre food sources beneath the snow by clearing it away with their antlers, but they cannot break through the hard ice.Without access to the food in winter, calves are being born far lighter than they should be.Numbers of reindeer have also soared in the past 20 years, meaning that those which are born are facing greater competition for food.“The implications are that there may well be more smaller reindeer in the Arctic in the coming decades, but possibly at risk of catastrophic die-offs because of increased ice on the ground,” said Professor Albon.According to Christmas folklore, Santa Claus uses a team of eight reindeer to transport him around the world in a single evening.Based on the 1923 poem a Visit from St Nicholas – though more commonly known as The Night Before Christmas – these are Dasher, Dancer, Prancer, Vixen, Comet, Cupid, Donner and Blitzen.In the imaginations of many, however, Rudolph has been added as an honorary ninth member of the team, thanks to the enduring popularity of the song Rudolph the Red-Nosed Reindeer.Despite the gloomy findings, reindeer appear to be suffering less from the impact of climate change than some other arctic species.Last week the scientists warned that a third of the world’s polar bears could disappear in the next 40 years to to melting Arctic sea ice. Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily  Front Page newsletter and new  audio briefings. Dragging a sleigh laden with enough presents for the world’s children – not to mention a famously portly white-bearded gentleman – can be no easy feat.But, since time immemorial, this crucial Christmas Eve duty has been performed with distinction by a team of beloved reindeer.Soon, however, Santa Claus may have to start looking around for a stronger type of animal, as new research reveals the species is becoming increasingly puny. A 16-year survey on the arctic Norwegian island of Svalbard found the reindeer there have declined in weight by an alarming 12 per cent.The reduction in average body-mass is being blamed on global warming.In research presented today at a meeting of the British Ecological Society in Liverpool, scientists will explain how rising temperatures are depriving female reindeer of nutrients during important phases of gestation.Snow in Svalbard typically covers the ground for eight months of the year, which, combined with low temperatures, limits grass growth to June and July.But as summer temperatures have increased by around 1.5C, pastures have become more productive, allowing female reindeer to gain more weight by the autumn and therefore to conceive more calves.last_img read more

admin September 25, 2019 xzatoksixeja Leave a Comment

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Assaulted Essequiban forced to watch girlfriend being raped GDF ranks implicated

Two members of the Guyana Defence Force (GDF) attached to the sixth Infantry Battalion at Anna Regina, Essequibo Coast were placed under close arrest following their implication in a robbery/rape committed on a couple on Saturday evening.Based on reports received, the two ranks were accused of raping a young girl while her boyfriend was forced to look on in the vicinity of the Anna Regina Community Centre Ground.It is believed that the incident occurred at about 23:40h. The two young people reportedly went to the venue for a walk.While there, they were reportedly attacked by the two GDF ranks who allegedly beat the young man, took away his money, gold chain and demanded that his girlfriend have sex with them, if not they would rape him.At first, this demand was shut down but the two ranks reportedly retaliated by hitting the young man mercilessly.She finally conceded to the demand. This publication understands that the two men took turns violating the young girl as she wept bitterly and asked them to stop.After the ordeal, the two young people reported that matter to the police station.At the police station, they were reportedly told that there were no ranks available to search the area.The family members took it upon themselves to look for the two perpetrators. Upon seeing the angry mob, the two men reportedly escaped.The two young people were taken to hospital where the young lady was admitted a patient.The police finally took statements from the two traumatized young people and an investigation was launched.The GDF in a release stated that it will give the necessary support to the Guyana Police Force as the investigations continue into the heinous crime. Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)RelatedGDF ranks who allegedly raped teenage girl, assaulted her boyfriend arrestedOctober 17, 2018In “Crime”GDF ranks implicated in crimes to face full brunt of the law- Chief of Staff (ag)November 1, 2018In “Crime”Mother details horrific story of daughter’s rape at the hands of Guyana’s DefendersFebruary 1, 2017In “Crime” read more

admin September 25, 2019 xzatoksixeja Leave a Comment

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Tributes flow for lost angel

first_img Facebook Twitter: @NeosKosmos Instagram Perhaps you aren’t ready yet, To have to say goodbye. Perhaps you’ve thought of things you wished you said, Well so have I. For one thing I’d have told you, not to worry about me. I’m with The Lord in heaven now, You knew that’s where I’d be. I’m sorry that you’re feeling sad, For I am so happy now, I’ve asked The Lord to ease the hurt and comfort you somehow. It’s hard at the beginning, But I know you’ll make it through. I hope it helps to know that I’ll be waiting here for you.That was the poem that adorned Priscilla Mallis’ facebook page following her untimely death last Friday night. Priscilla was only 19 when she died after her brave lifelong battle with Cystic Fibrosis. Her facebook page has been filled with moving tributes from family and friends who remember a girl – who in the face of anguish and adversity – kept smiling. A girl who never once lost hope even though the odds were stacked so high against her. Three months after her birth, Priscilla was diagnosed with this life threatening condition. Commonly known as CF, Cystic Fibros is the most common life threatening, recessive genetic condition affecting Australian children. In January this year, Priscilla was the recipient of a lung transplant, but sadly, not even this could save the brave young lady. At 1:30 am, Friday 9 August, Priscilla lost her fight. Tomorrow, family, friends and members of the Greek community mourned and remembered this bright beautiful angel that was taken away from us so early.RIP Priscilla Mallis.last_img read more

admin September 21, 2019 xzatoksixeja Leave a Comment

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Shopping with the Deltas

first_imgThe Washington Alumnae Chapter of Delta Sigma Theta Sorority in partnership with the Washington D.C. Alumnae Foundation are scheduled to host a shopping experience with Alex & Ani. The event, which is open to the public, will be held at the National Harbor, 180-A Waterfront Street on Dec. 14 from 5 p.m. to 8 p.m. Fifteen percent of the proceeds go towards scholarships.last_img

admin September 1, 2019 xzatoksixeja Leave a Comment

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Precision Oncology Could Be Tailormade for Metastatic Prostate Cancer

first_img News | Radiation Therapy | August 16, 2019 Drug Accelerates Blood System’s Recovery After Radiation, Chemotherapy A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem… read more February 29, 2016 — Metastatic prostate cancer, where better therapeutic strategies are desperately needed, appears to be tailor-made for precision oncology, according to a new study by researchers at Fred Hutchinson Cancer Research Center in Seattle. They found that a single metastasis within an individual patient can provide consistent molecular information to help guide therapy in metastatic prostate cancer.The research showed that though they are very complex, prostate cancer metastases within an individual patient are strikingly similar in their molecular characteristics, while metastases from different patients have very dissimilar characteristics. This suggests that patients could benefit from individualized therapy and that a single biopsy will likely provide enough information to guide that therapy.Evidence has been growing that molecular characteristics of original or primary tumors, which often take decades to develop, can exhibit substantial heterogeneity, or variation in the composition of cancer-causing genes in different areas within the tumors. In contrast, scientists have little information about the diversity to be found in metastases, the tumors that arise from cells that have broken free and traveled far from the first tumor. When cancer spreads, it often relocates to several distant sites within an individual, leading to the question of whether obtaining a sample of one metastatic site would provide information that is relevant for guiding therapy of the other sites of spread. Uniformity among metastases within a patient would ensure that therapies designed to target a specific metastasis would likely treat all of a patient’s metastases.To work effectively, precision oncology requires two things: that tumors from different individuals are very different in their oncogenic drives and therapeutic susceptibilities, and that tumors within an individual are quite uniform. This means that researchers can develop a therapy that can effectively target all of a specific patient’s tumors, even if it is not effective for other patients.Primary tumors, which can be very heterogeneous, can be managed by surgery or radiation. There are few effective treatments for metastatic cancer. Patients with metastatic disease need different interventions — but these will only work if the metastases are not heterogeneous. Peter S. Nelson, M.D., a member of the Human Biology, Clinical Research and Public Health Sciences divisions at Fred Hutch, and his team set out to determine whether prostate cancer metastases meet the conditions for effective precision oncology: homogeneous within patients, but heterogeneous between patients.Primary or metastatic tumors from 176 men were removed and analyzed for various genetic and genomic alterations, such as copy number alterations, gene expression and whole-exome sequencing. (Not all tumors were assessed all three ways.)The researchers found limited genomic diversity within patients, meaning that a single metastasis provided complete molecular and genetic information. The presumptive driver mutations generally occurred within all metastases tested from a single individual. The mutations that were found to be unique to specific tumors were generally not predicted to be detrimental. Substantial differences in genomic alterations were found between individuals.“If you look in multiple metastases within a given patient, they’re actually very, very similar,” said Nelson, the study’s senior and corresponding author. “They’re not identical, but in terms of the key features of a cancer that would inform how best to treat that cancer we can feel generally confident, at least with prostate carcinoma, that if you did sample a single tumor, you could make clinical decisions based on what you find.”The insights of the study were not used to guide therapy, only to suggest that this strategy looks promising.The work was funded by the National Institutes of Health (Pacific Northwest Prostate Cancer SPORE grant), the U.S. Department of Defense, a Fred Hutchinson Cancer Research Center Solid Tumor Translational Research Award and the Prostate Cancer Foundation. The authors declare no competing financial interests.For more information: FacebookTwitterLinkedInPrint分享 News | Mammography | August 14, 2019 Imago Systems Announces Collaboration With Mayo Clinic for Breast Imaging Image visualization company Imago Systems announced it has signed a know-how license with Mayo Clinic. The multi-year… read more News | Prostate Cancer | February 29, 2016 Precision Oncology Could Be Tailor-made for Metastatic Prostate Cancer Study finds tissue from a single metastasis could provide all the information needed to custom-design therapy for patients with advanced prostate cancer News | Proton Therapy | August 08, 2019 MD Anderson to Expand Proton Therapy Center The University of Texas MD Anderson Cancer Center unveiled plans to expand its Proton Therapy Center during a… read more News | Artificial Intelligence | August 13, 2019 Artificial Intelligence Could Yield More Accurate Breast Cancer Diagnoses University of California Los Angeles (UCLA) researchers have developed an artificial intelligence (AI) system that… read more Technology | Interventional Radiology | August 16, 2019 Profound Medical Receives U.S. FDA 510(k) Clearance for Tulsa-Pro Profound Medical Corp. announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to… read more Related Content Catalyst PT image courtesy of C-RAD News | Brachytherapy Systems | August 14, 2019 Efficacy of Isoray’s Cesium Blu Showcased in Recent Studies August 14, 2019 — Isoray announced a trio of studies recently reported at scientific meetings and published in medica read more center_img Image courtesy of Imago Systems News | Pediatric Imaging | August 14, 2019 Ultrasound Guidance Improves First-attempt Success in IV Access in Children August 14, 2019 – Children’s veins read more News | Neuro Imaging | August 16, 2019 ADHD Medication May Affect Brain Development in Children A drug used to treat attention-deficit/hyperactivity disorder (ADHD) appears to affect development of the brain’s… read more Images of regions of interest (colored lines) in the white matter skeleton representation. Data from left and right anterior thalamic radiation (ATR) were averaged. Image courtesy of C. Bouziane et al. The MD Anderson Proton Therapy Center expansion is expected to be completed in 2023. Rendering courtesy of Stantec. News | Patient Positioning Radiation Therapy | August 15, 2019 Mevion and C-RAD Release Integration for Improved Proton Therapy Treatment Quality Mevion Medical Systems and C-RAD announced the integration between the C-RAD Catalyst PT and the Mevion S250i proton… read more Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right). Credit: UCLA Broad Stem Cell Research Center/Nature Communications News | Radiation Therapy | August 15, 2019 First Patient Enrolled in World’s Largest Brain Cancer Clinical Trial Henry Ford Cancer Institute is first-in-the-world to enroll a glioblastoma patient in the GBM AGILE Trial (Adaptive… read more last_img read more

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Tariq Aziz top aide to Saddam Hussein dies in hospital

first_img New Valley school lets students pick career-path academies BAGHDAD (AP) — Tariq Aziz, the debonair Iraqi diplomat who made his name by staunchly defending Saddam Hussein to the world during three wars and was later sentenced to death as part of the regime that killed hundreds of thousands of its own people, has died in a hospital in southern Iraq, officials said. He was 79.Aziz died on Friday afternoon after he was taken to the al-Hussein hospital in the city of Nasiriyah, about 320 kilometers (200 miles) southeast of Baghdad, according to the provincial governor, Yahya al-Nassiri. Aziz had been in custody in a prison in the south, awaiting execution. Aziz was the highest-ranking Christian in Saddam’s regime was its international face for years. He was sentenced in October 2010 to hang for persecuting members of the Shiite Muslim religious parties that now dominate Iraq.A Baghdad government official confirmed the death of Aziz. He spoke on condition of anonymity because he was not authorized to talk to reporters.Al-Nassiri, the governor of Dhi Qar province where Nasiriyah is the capital, said Aziz’s wife Violet had visited him on Thursday in prison and spent about an hour with him. Aziz had suffered from diabetes and high blood pressure for a long time, and he was a chain smoker, the governor added. Local Iraqi authorities on Friday told the family it can take Aziz’s body from the hospital morgue.The only Christian among Saddam’s inner circle, Aziz’s religion rescued him from the hangman’s noose that was the fate of other members of the top regime leadership.After he was sentenced to death, the Vatican asked for mercy for him as a Christian. Iraq’s president at the time, Jalal Talabani, then refused to give the death sentence his required signature, citing Aziz’s age and religion. Top Stories Milstead says best way to stop wrong-way incidents is driving sober The difference between men and women when it comes to pain Al-Nassiri said that Aziz was immediately taken to the hospital when the heart attack occurred. “The medical staff did their best to rescue him, but they failed. It is God’s will,” he added.Even before he was sentenced, the ailing Aziz appeared to know that he would die in custody. He had had several strokes while in custody undergoing trial multiple times for various regime crimes.“I have no future. I have no future,” Aziz told The Associated Press, looking frail and speaking with difficulty because of a recent stroke, in a jailhouse interview in September 2010. At that stage, he had been sentenced to more than two decades in prison.“I’m sick and tired but I wish Iraq and Iraqis well,” he said.Elegant and eloquent, Aziz spoke fluent English, smoked Cuban cigars and was loyal to Saddam to the last, even naming one of his son’s after the dictator. His posts included that of foreign minister and deputy prime minister, and he sat on the Revolutionary Command Council, the highest body in Saddam’s regime.His main role was as the regime’s go-to man to communicate with the West. To the world, he was one of the most recognizable faces from Iraq during Saddam’s rule: silver haired, with a mustache and trademark dark-rimmed glasses. A skilled operator in the halls of the United Nations, he was the regime’s front-man in dealing with U.N. inspectors trying to track and assure the dismantling of Saddam’s weapons of mass destruction. Former Arizona Rep. Don Shooter shows health improvement Comments   Share   Arizona families, Arizona farms: A legacy of tradition embracing animal care and comfort through modern technologycenter_img His interlocutors variously described him as courtly, articulate, arrogant and unhesitant to make even the most preposterous denials of evidence put before him by inspectors about weapons programs.“He didn’t agree with our basic tasks and I didn’t agree with his tasks to hide and mislead us. But I think we respected each other,” Rolf Ekeus, head of the inspectors from 1991 to 1997, later said of Aziz.As bombs rained down on Baghdad during the U.S.-led 2003 invasion, Aziz said of American forces, “We will receive them with the best music they have ever heard and the best flowers that have ever grown in Iraq … We don’t have candy; we can only offer them bullets.”His freedom ended shortly afterward. The U.S. military knocked on his door in Baghdad on April 24, 2003, and he surrendered without resistance.Still, his prominence as an international spokesman — and his outsider status as a Christian in a Sunni Muslim-dominated regime — gave supporters fuel to argue that he was not a real decision-maker in Saddam’s regime and was less to blame in the torture and bloody crackdowns it inflicted on Iraqis.Aziz was born to a Chaldean Catholic family in Tell Kaif, Iraq, in 1936. He studied English literature at Baghdad College of Fine Arts and became a teacher and journalist. He joined the Baath Party in 1957, working closely with Saddam to overthrow British-imposed monarchy. FILE – FILE – In this Sept. 5, 2010 file photo, Tariq Aziz, Saddam Hussein’s long time foreign minister, speaks to the Associated Press in Baghdad, Iraq. Officials say Aziz has died in a hospital in southern Iraq on Friday, June 5, 2015. (AP Photo/Hadi Mizban, File) Ex-FBI agent details raid on Phoenix body donation facility 5 things to look for when selecting an ophthalmologist Saddam took charge in 1979. Aziz was deputy prime minister a year later, when attackers hurled a grenade at him in downtown Baghdad. Several people were killed; Aziz was injured. It was one of several attacks Saddam blamed on Iran — part of his justification for the expulsion of large numbers of Shiite Muslims and Iraq’s 1980 invasion of Iran.Aziz was instrumental in restoring diplomatic relations with the United States in 1984, after a 17-year break. At the time, Washington backed Iraq as a buffer against Iran’s Islamic extremism.That changed after Iraq’s invasion of Kuwait in 1990. Aziz met in January 1991 with then-Secretary of State James A. Baker in Geneva in a failed attempt to prevent the Gulf War, and the U.S. broke off ties with Saddam’s government for good. He also met with the late Pope John Paul II at the Vatican just weeks before the March 2003 invasion in a bid to stop it.Years later in court, Aziz again defended Saddam.A star defense witness for his former boss in 2006, a thin and pale-looking Aziz in checkered pajamas — a far cry from the designer suits he once sported — insisted Saddam had no choice but to crack down in the Shiite town of Dujail after a 1982 shooting attack on the president’s motorcade there blamed on Shiite opponents. Aziz is survived by his wife and two sons, Ziad and Saddam, who live in Jordan and who had long lobbied that he be allowed to receive medical treatment outside Iraq.Copyright © The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed. Sponsored Stories “If the head of state comes under attack, the state is required by law to take action,” said Aziz.And in the trial of six former Saddam officials charged with the 1980s crackdown on Kurds that killed an estimated 100,000 people, Aziz claimed, “There was no genocide against the Kurds … Those defendants were honest officers who defended their country and fought Iran.”Aziz himself stood trial in seven cases — nearly all on charges of crimes against humanity related to Saddam’s campaigns against Shiite political parties and Kurds. He was convicted in all but two, and sentenced to death by hanging in October 2010 for his involvement in the former regime’s bloody persecution of Shiites.As his death verdict was read in court, Aziz sat alone and quiet, and grasped a handrail surrounding the defendant’s box. By that time, he had suffered a stroke in jail that had left him badly weakened and temporarily mute.But even as he was ordered executed, Aziz gained a powerful diplomatic ally. The Vatican asked that Aziz’s life be spared, saying mercy would encourage reconciliation and the rebuilding of peace and justice in Iraq. The Vatican’s plea picked up support among several other European diplomats from nations that also oppose the death penalty — though few had made much pressure to stop earlier executions of other, Muslim members of Saddam’s regime.last_img read more

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Travel as you like with IRCTCs Jyamon Khushi Beran scheme

first_imgThe Indian Railway Catering and Tourism Corporation (IRCTC), Eastern Zone has launched the ‘Jyamon Khushi Beran’ scheme to cater to tailor-made short trips for fewer people.Debashis Chandra, General Manager, IRCTC (east) group, explained, “Our normal tours are arranged for groups of 25-30 people and last for at least 6-7 days. Nowadays, there are many couples who want 2-3 day outings with their children to destinations that are not run of the mill. We want to target such people. For instance, families may want to visit Manas in Assam or Gopalpur-Bhittarkanika in Odisha. We will arrange everything, from their travel by air or rail to accommodation and sightseeing. Our plan is to go in for the ‘wish marketing’ concept instead of selling tours planned by us.”To schedule a dream trip, one only needs to call up IRCTC or send a mail. Executives will call back to find out the requirements after which it will take 7-10 days to work out details and give various options to the travellers.“Our aim is to exploit the immense potential that the eastern sector has. People now want to travel to the north eastern states. We also want to tap the adventure tourism market. We are in plans to arrange for trekkers’ huts and forest bungalows. The monsoons are a very good time to travel for those who want small trips, particularly to forests that remain open. At this time, accommodation is normally cheaper than the normal tourist seasons,” added Chandra.Apart from the popular tours to foreign destinations, IRCTC has also divulged plans to foray into the field of medical tourism for which it will tie-up with many hospitals and arrange for the travel, stay and treatment for outstation patients.last_img read more

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Ginnie Mae Pres on Growth Our Systems Are Volume Agnostic

first_img Share Ginnie Mae Pres on Growth: ‘Our Systems Are Volume Agnostic’ Flood Insurance Ginnie Mae House Financial Services Committee Housing Reform michael bright 2017-11-29 David Wharton November 29, 2017 786 Views center_img Wednesday morning, the House Financial Services Committee held a hearing entitled “Sustainable Housing Finance: The Role of Ginnie Mae in the Housing Finance System.” Michael R. Bright,  Acting President, Government National Mortgage Association (Ginnie Mae), appeared before the Committee to discuss the challenges currently facing Ginnie Mae, as well as what challenges and adaptations await it in the future.Much of the discussion focused on a paper Bright co-wrote with former FHFA Acting Director Ed DeMarco in September 2016. Bright and DeMarco’s proposal would “end the conservatorships, reconstitute Fannie Mae and Freddie Mac as lender-owned mutuals, and build on the credit risk transfer (CRT) initiative to create a private market for mortgage credit risk while preserving a government-guaranteed rates market for mortgage-backed securities.” In addition, Ginnie Mae would be removed from the Department of Housing and Urban Development (HUD) and converted into a standalone government corporation like FDIC, “with authority over its own budget, hiring, and compensation.”Obviously, making dramatic changes to Ginnie could be a cause for concern to some. As Rep. Brad Sherman (D-California) put it, “I don’t buy the idea that ‘if it’s not broke, don’t fix it,’ because sometimes you can make things better. But if it’s not broke, don’t break it.”Even though he proposes changes, Bright had plenty of positive things to say about Ginnie, and the things it does well. “At a very high level, the Ginnie Mae wrap works because we do two things effectively. First, we are transparent about our rules and our processes with our investors. And second, we work hard to police our program.”Whether or not Ginnie undergoes that sort of large-scale change in the future, there are plenty of challenges closer at hand. With the mortgage market moving to modernize and embrace e-mortgages, Ginnie Mae is moving to follow. While Bright conceded there were various upgrade and architecture challenges posed by this, he said Ginnie has those upgrades slated for 2018.Rep. Dennis Ross (R-Florida) asked what impact this year’s damaging flood season had on Ginnie, especially given how many affected properties either did not have flood insurance or had insufficient flood insurance. “That is not an insignificant problem,” Bright said, noting that 150,000 Ginnie properties had been affected by the floods and did not have sufficient flood insurance.Bright continued, saying, “If you have a property that has been damaged through a flood, and the property cannot get into a conveyable condition to file a claim with FHA, it does raise the risk that the issuer, if they’re concentrated in that particular geographic location, could have an insolvency situation.” Bright said they were currently analyzing the total impacts of the floods.Rep. Randy Hultgren (R-Illinois) asked Bright if he had any concerns about Ginnie’s recent or expected growth. “We’re very aware that with greater size comes greater risk, especially when your base is shifting,” Bright said. However, he said that he didn’t believe growth was concerning in and of itself, as Ginnie has an array of risk-management tools and the processes tend to work the same way regardless. “Mechanically speaking, our systems are volume agnostic,” Bright said.Looking forward, Bright said Ginnie’s focus over the next few years would be ensuring that issuers have access to the liquidity they need, having a solid idea of the value of the MSRs involved, and having a game plan for what they would do with the MSR in the event of a problem. “It’s not so much value as the quality of your counterparty that matters,” Bright said.You can watch the full video of the House Financial Services Committee hearing below. in Daily Dose, Featured, Government, journal, Newslast_img read more

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Binzel called the A

Binzel called the Asteroid Return Mission (or ARM) “the emperor with no clothes.

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have been followi

I have been following a secular and progressive ideology for the last 35 years since I left school. The last line of this page is shocking & unacceptable where they question Faesal’s “integrity & honesty”.

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So period, and lungs that intensified with each attack, the Delta-state born Okoli said he kept the N70. read more

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